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RECRUITING
NCT03504800

OCT in Diagnosis of Irregular Corneas

Sponsor: Oregon Health and Science University

View on ClinicalTrials.gov

Summary

This main goal of this study is to improve the detection, classification, monitoring, and treatment of irregular corneas due to keratoconus, warpage, dry eye, scar, stromal dystrophies, and other corneal conditions. The primary goal will be achieved by using optical coherence tomography (OCT) to: 1. Develop an OCT-based system to classify and evaluate corneal-shape irregularities. 2. Develop OCT metrics for more sensitive detection of keratoconus progression. 3. Develop OCT-and-topography guided phototherapeutic keratectomy (PTK) for irregular corneas.

Official title: Optical Coherence Tomography-Aided Differential Diagnosis and Treatment of Irregular Corneas

Key Details

Gender

All

Age Range

14 Years - 85 Years

Study Type

OBSERVATIONAL

Enrollment

445

Start Date

2018-05-01

Completion Date

2031-02-28

Last Updated

2025-09-09

Healthy Volunteers

Yes

Interventions

DEVICE

Optical Coherence Tomography

This device will be used to tightly classify corneal irregularities and determine eligibility of candidates from Group A into Groups B \& C.

Locations (1)

Humberto Martinez

Portland, Oregon, United States