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RECRUITING
NCT03504956
NA

Coronary Atherosclerosis T1-Weighted Characterization (CATCH)

Sponsor: Cedars-Sinai Medical Center

View on ClinicalTrials.gov

Summary

This study proposes to develop an MRI technique named Coronary Atherosclerosis T1-weighed Characterization (CATCH) that will improve the quality and reliability of coronary atherosclerosis evaluation, as well as simplify the scanning process and significantly shorten imaging time compared with conventional imaging methods.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

150

Start Date

2018-07-30

Completion Date

2026-12-31

Last Updated

2025-08-14

Healthy Volunteers

Yes

Interventions

DEVICE

Cardiac MRI

MRI with/without administration of a contrast agent and beta-blocker based upon the stage of method development, if no contraindications are present.

DRUG

Contrast

The intravenous gadolinium based contrast agent to be used in this study is Gadavist (up to 0.2 mmol/kg).

DRUG

Beta blocker

Based upon the focus of the study at the time of the scan, a beta- blocker (metoprolol), in pill form based upon blood pressure and heart rate, may be administered to some subjects to improve the heart's ability to relax and slow the heart rate. The slower heart rate may improve image quality and lessen motion artifact.

Locations (1)

Cedars-Sinai Medical Center

Los Angeles, California, United States