Clinical Research Directory

Inclusion Criteria: * Patients with painful Ledderhose disease. The pain score measured with the VAS score and is at least 2 on the 11-point scale (0 = no pain to 10 = worst imaginable pain). * Age ≥ 18 years * WHO performance status 0, 1 or 2 (Appendix, section 18) * Before patient randomisation, written informed consent must be given according to ICH/GCP, and WMO requirements. * Controlling the Dutch language (speaking and reading). * Able and willing to complete quality of life questionnaires in Dutch * Must be accessible for treatment follow-up Exclusion Criteria: * Surgical intervention before for Ledderhose disease * Previous radiation treatment for Ledderhose disease * Any psychological, familial, sociological or geographical condition potentially hampering compliance with the study protocol and follow-up schedule * Not able to lay prone for at least fifteen minutes * Females who are pregnant at entry or who want to become pregnant within six months.