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Ketogenic Diet to Improve Neuro-recovery
Sponsor: Ohio State University
Summary
The purpose of this project is to determine if 5 weeks of ketogenic (KD, high-fat) diet vs. standard diet (SD) significantly improves motor and sensory function, glycemic function, and functional independence in patients with spinal cord injury.
Official title: Evaluation of a Ketogenic Diet for Improvement of Neurological Recovery in Individuals With Acute Spinal Cord Injury
Key Details
Gender
All
Age Range
19 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2019-05-09
Completion Date
2026-01-01
Last Updated
2025-07-29
Healthy Volunteers
No
Conditions
Interventions
Ketogenic Diet
Enteral feeding via nasogastric (NG) or nasojejunal (NJ) tubes with ketogenic diet will start within 72 hours of injury and solid feeding will start as soon as the patient is able to swallow. This diet is a high-fat, low-carbohydrate diet (lipid to carbohydrate + protein ratio of 3:1) that will include ≈75% total energy as fat, ≈20% as protein, and ≈5% as carbohydrate and fiber.
Standard Diet
Enteral feeding via nasogastric (NG) or nasojejunal (NJ) tubes with SD diet will start within 72 hours of injury and solid feeding will start as soon as the patient is able to swallow. This diet includes ≈35% total energy as fat, ≈27% as protein, and ≈44% as carbohydrate and fiber.
Locations (1)
Ohio State University Hospital
Columbus, Ohio, United States