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COMPLETED
NCT03518801
PHASE2

Cannabidiol and Prolonged Exposure

Sponsor: VA Office of Research and Development

View on ClinicalTrials.gov

Summary

The trial will include a randomized control trial to evaluate the efficacy of using Cannabidiol (CBD), a non-intoxicating cannabinoid, as an adjunctive to Prolonged Exposure therapy (PE). The trial will compare PE + CBD to PE + placebo in a sample of 136 military Veterans with PTSD at the VA San Diego Medical Center. The study represents the logical and innovative next step for augmenting existing treatments and developing novel pharmacotherapy for PTSD. Findings from the proposed RCT will inform clinical practice and policy by investigating whether administration of CBD in the context of PE therapy will improve treatment outcomes for military Veterans with PTSD.

Official title: Cannabidiol as an Adjunctive to Prolonged Exposure for the Treatment of PTSD

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

136

Start Date

2019-10-01

Completion Date

2025-09-30

Last Updated

2026-05-08

Healthy Volunteers

No

Conditions

Interventions

BEHAVIORAL

Prolonged Exposure

psychotherapy

DRUG

Cannabidiol

active medication

DRUG

placebo

non-active medication

Locations (1)

VA San Diego Healthcare System, San Diego, CA

San Diego, California, United States