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Cannabidiol and Prolonged Exposure
Sponsor: VA Office of Research and Development
Summary
The trial will include a randomized control trial to evaluate the efficacy of using Cannabidiol (CBD), a non-intoxicating cannabinoid, as an adjunctive to Prolonged Exposure therapy (PE). The trial will compare PE + CBD to PE + placebo in a sample of 136 military Veterans with PTSD at the VA San Diego Medical Center. The study represents the logical and innovative next step for augmenting existing treatments and developing novel pharmacotherapy for PTSD. Findings from the proposed RCT will inform clinical practice and policy by investigating whether administration of CBD in the context of PE therapy will improve treatment outcomes for military Veterans with PTSD.
Official title: Cannabidiol as an Adjunctive to Prolonged Exposure for the Treatment of PTSD
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
136
Start Date
2019-10-01
Completion Date
2025-09-30
Last Updated
2026-05-08
Healthy Volunteers
No
Conditions
Interventions
Prolonged Exposure
psychotherapy
Cannabidiol
active medication
placebo
non-active medication
Locations (1)
VA San Diego Healthcare System, San Diego, CA
San Diego, California, United States