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DNA Methylation and Vascular Function
Sponsor: University of Illinois at Chicago
Summary
The main objective is to examine DNA hypomethylation as an underlying mechanism for the increased production of inflammatory cytokines and the impaired vascular function in obese individuals and as a potential target for nonpharmacological preventive/therapeutic interventions such as aerobic exercise.
Official title: DNA Methylation and Vascular Function in Obesity: Role of Exercise and Weight Loss
Key Details
Gender
All
Age Range
18 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2019-10-11
Completion Date
2026-08-31
Last Updated
2025-09-15
Healthy Volunteers
Yes
Conditions
Interventions
Exercise training
Twelve weeks of aerobic exercise training
Locations (1)
University of Illinois at Chicago
Chicago, Illinois, United States