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NCT03531073

Multicentre ObservatioNal Initiative in Treat to Target Outcomes in Psoriatic Arthritis

Sponsor: University of Oxford

View on ClinicalTrials.gov

Summary

MONITOR is a cohort study recruiting patients with a new diagnosis of psoriatic arthritis (PsA) which will establish outcomes using a pragmatic feasible 'treat to target' approach in a real-life clinic population. It is the central cohort for a planned Trials Within Cohorts (TWiCs) design which will test alternative therapies and interventions in embedded clinical trials comparing outcomes to those receiving "standard care" in the cohort.

Official title: A Multicentre Observational Psoriatic Arthritis Cohort Study Addressing Real-life Outcomes of a Treat to Target Approach in Routine Clinical Practice.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

446

Start Date

2018-04-18

Completion Date

2024-12-31

Last Updated

2026-06-22

Healthy Volunteers

No

Interventions

DRUG

Methotrexate

This study is observational and patients will receive treatment for their psoriatic arthritis as clinically indicated. As per standard practice in this observational cohort, patients are most likely to be treated with methotrexate as the most common first line therapy in PsA. This cohort is the basis of a TWiCs (Trials Within Cohorts) study design and interventional studies will be nested within this in future. Whilst the cohort will receive treatment for their PsA as part of their routine clinical care, this treatment will be decided according to routine care and not protocolised.

Locations (1)

Oxford University Hospitals NHS Trust

Oxford, Oxfordshire, United Kingdom