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COMPLETED
NCT03537742
PHASE2

Cardiac Allograft Vasculopathy Inhibition With Alirocumab

Sponsor: Stanford University

View on ClinicalTrials.gov

Summary

The focus of this study is to test the safety and efficacy of the PCSK9 inhibitor, alirocumab when administered early after heart transplantation (HT).The main objective of this project is to test the safety and impact on cardiac allograft vasculopathy (CAV) of alirocumab when given early after HT.

Official title: PCSK9 Inhibition After Heart Transplantation

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

114

Start Date

2019-05-13

Completion Date

2025-07-11

Last Updated

2026-08-18

Healthy Volunteers

No

Conditions

Interventions

BIOLOGICAL

alirocumab

alirocumab 150mg Subcutaneous

BIOLOGICAL

placebo

placebo to match alirocumab

Locations (1)

Stanford University

Stanford, California, United States