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RECRUITING
NCT03549559
NA
Imaging Histone Deacetylase in the Heart
Sponsor: Massachusetts General Hospital
View on ClinicalTrials.gov
Summary
The overall goal of this PET-MR imaging trial is to evaluate 11C-Martinostat, a histone deacetylase targeted radioligand, in patients with aortic stenosis, individuals with diabetes, and healthy volunteers.
Official title: Imaging of Histone Deacetylase in the Heart
Key Details
Gender
All
Age Range
18 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
96
Start Date
2018-09-07
Completion Date
2026-09-01
Last Updated
2025-12-22
Healthy Volunteers
Yes
Conditions
Interventions
DRUG
11C-Martinostat
Imaging probe for evaluating the activity of histone deacetylase in the heart
DEVICE
PET-MRI
Siemens PET-MR Scanner (Biograph MMR)
Locations (1)
Massachusetts General Hospital
Boston, Massachusetts, United States