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RECRUITING
NCT03549559
NA

Imaging Histone Deacetylase in the Heart

Sponsor: Massachusetts General Hospital

View on ClinicalTrials.gov

Summary

The overall goal of this PET-MR imaging trial is to evaluate 11C-Martinostat, a histone deacetylase targeted radioligand, in patients with aortic stenosis, individuals with diabetes, and healthy volunteers.

Official title: Imaging of Histone Deacetylase in the Heart

Key Details

Gender

All

Age Range

18 Years - 85 Years

Study Type

INTERVENTIONAL

Enrollment

96

Start Date

2018-09-07

Completion Date

2026-09-01

Last Updated

2025-12-22

Healthy Volunteers

Yes

Interventions

DRUG

11C-Martinostat

Imaging probe for evaluating the activity of histone deacetylase in the heart

DEVICE

PET-MRI

Siemens PET-MR Scanner (Biograph MMR)

Locations (1)

Massachusetts General Hospital

Boston, Massachusetts, United States