Clinical Research Directory

Inclusion Criteria: * Children under 16 years of age coming for a consultation for a beta-lactam oral reintroduction test. Exclusion Criteria: * Refusal of the legal representatives of the subject for their child to participate in the study, * If his age permits, refusal of the subject to participate in the study, * Subject aged over 16, * Pregnancy, * Absence of affiliation of the subject to a social security scheme, * Skin tests with incriminated beta-lactam already made before the consultation, * Existence of contraindications to the realization of oral reintroduction drug test with the suspected antibiotic, * Existence of criteria in the initial reaction suggestive of a non-low risk of IgE-mediated or delayed hypersensitivity to the incriminated beta-lactam, Taking antihistamine, corticosteroids or beta-blockers within 5 days prior to the oral reintroduction drug test, * Travel abroad of the child scheduled within 7 days of the oral reintroduction drug test.