Clinical Research Directory

Inclusion Criteria: * The tremor diagnosis, disability and medically refractory status are agreed upon by at least two movement disorder trained physicians (neurologists and/or neurosurgeons). * The patient is deemed suitable for surgical therapy for tremor with VIM targeting. * The patient is willing to participate in the study and provides written informed consent. * The patient is able to clearly communicate clinical findings with the clinical team. * The patient is willing to participate in at least one follow-up visit at 3 or 6 months. * In order to maintain uniformity of image acquisition only patients undergoing imaging with the 3T MRI at The Ohio State University Wexner Medical Center will be included. Exclusion Criteria: * Medically unstable - uncontrolled hypertension, coronary artery disease, significant pulmonary problems, active history of bleeding disorders or anticoagulation. * Other diagnoses of tremor like Parkinson's disease, traumatic tremor, dystonic tremor, and/or tremor associated with multiple sclerosis * Unwilling or unable to undergo awake tremor surgery. * Tremor patients undergoing surgery with targets other than the VIM. * Significant motion artifact in imaging. * Unable to undergo 3T MRI imaging.