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Secondary Sclerosis Cholangitis Prospective
Sponsor: Medical University of Graz
Summary
SC-CIP is increasing in patients after critical illness. Pathogenesis is still largely unclear. Gut microbiome composition, gut permeability, bacterial translocation, inflammation and/or genetic variants contribute to the pathogenesis The aim of this project is to study gut microbiome composition, gut permeability, bacterial translocation, inflammation, bile acid composition and genetic polymorphisms by conducting a prospective cohort study in patients with a high risk to develop SC-CIP.
Official title: Secondary Sclerosing Cholangitis in Critically Ill Patients (SC-CIP): A Prospective Cohort Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
380
Start Date
2018-07-20
Completion Date
2027-12
Last Updated
2024-10-09
Healthy Volunteers
No
Locations (1)
Medical University Graz
Graz, Austria