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Pharmacogenomics of Asparaginase Induced Hepatotoxicity
Sponsor: University of Southern California
Summary
This pilot trial studies the impact of genetic information on developing liver damage caused by asparaginase in participants with newly diagnosed acute lymphoblastic leukemia. Testing saliva samples may help doctors find certain genetic markers that may predict whether participants will tolerate asparaginase, which is given as part of clinical care for acute lymphoblastic leukemia.
Official title: Pharmacogenomics of Age-Specific, Asparaginase-Induced Hepatotoxicity in Patients With Acute Lymphoblastic Leukemia
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
500
Start Date
2018-05-22
Completion Date
2026-12-31
Last Updated
2025-12-04
Healthy Volunteers
No
Conditions
Interventions
Biospecimen Collection
Undergo collection of saliva
Locations (1)
USC / Norris Comprehensive Cancer Center
Los Angeles, California, United States