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Behavioral Effects of Drugs: Inpatient (36) (Alcohol, Duloxetine, and Methylphenidate)
Sponsor: Craig Rush
Summary
This study will evaluate the behavioral effects of alcohol during maintenance on placebo, duloxetine, methylphenidate and duloxetine combined with methylphenidate using sophisticated human laboratory methods.
Official title: A Novel Drug Combination for Alcohol-Use Disorders: A Human Laboratory Study
Key Details
Gender
All
Age Range
21 Years - 55 Years
Study Type
INTERVENTIONAL
Enrollment
19
Start Date
2018-09-01
Completion Date
2023-03-15
Last Updated
2026-06-09
Healthy Volunteers
Yes
Conditions
Interventions
Alcohol
In each arm and during sessions, subjects will receive doses of alcohol designed to raise breath alcohol levels (BAL) to 0.03 g/dl.
Placebos
Subjects will receive oral placebo capsules.
Duloxetine (60 MG)
Subjects will receive 60-mg of oral duloxetine capsules.
Methylphenidate
Subjects will receive methylphenidate capsules.
Duloxetine (30 MG)
Subjects will receive 30-mg of oral duloxetine capsules.
Locations (1)
University of Kentucky
Lexington, Kentucky, United States