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Efficacy and Safety of 0.25% Timolol Gel in Enhancing Full Thickness Skin Grafts Healing and Cosmetic Outcomes
Sponsor: Brigham and Women's Hospital
Summary
The use of topical beta-blockers, such as 0.25% timolol, in promoting wound healing is currently emerging in the academic literature. The investigators will enroll 82 patients who have their skin cancer surgically removed resulting in the need of a full-thickness skin graft. The objective of this randomized safety study is to determine the safety and efficacy of 0.25% timolol in promoting wound healing in full-thickness skin grafts compared to standard of care.
Official title: Efficacy and Safety of 0.25% Timolol Gel in Enhancing Full Thickness Skin Grafts Healing and Cosmetic Outcomes: A Randomized, Controlled Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
10
Start Date
2019-01-02
Completion Date
2022-01-10
Last Updated
2026-06-09
Healthy Volunteers
Yes
Interventions
0.25% timolol gel with full-thickness skin grafts
Timolol 0.25% gel will be applied to wound bed immediately after surgery before dressing is applied.
Vaseline dressing
Vaseline will be applied to wound bed immediately after surgery before dressing is applied.
Locations (1)
Mohs and Dermatologic Surgery Center, Brigham and Women's Hospital
Boston, Massachusetts, United States