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Role of Frontal Cortex in the Pathophysiology of Gilles de la Tourette Syndrome (GTS)
Sponsor: University Hospital, Bordeaux
Summary
Tourette's syndrome (TS) is a debilitating and severe syndrome whose pathophysiology remains unclear. In order to precise the cortical regions involved in the generation of tics, investigators will realize an electroencephalogram (EEG) recording in the frontal cortex of TS patients in ecological conditions (EEG-holter). Activity changes will be correlated with event markers of tics and neurovegetative parameters. Statistical analyses will be compared between epochs of EEG recording with tics and without tics. The aim is to define the cortical regions involved in the genesis of tics in order to consider new targets for cortical stimulation.
Key Details
Gender
All
Age Range
12 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
14
Start Date
2018-02-02
Completion Date
2020-03-03
Last Updated
2026-05-20
Healthy Volunteers
No
Conditions
Interventions
Electroencephalographic recordings
24 hours of electroencephalographic recordings (EEG-Holter) of prefrontal activity of Tourette's syndrome (TS) patients in ecological conditions.
Locations (1)
CHU de Bordeaux
Bordeaux, France