Clinical Research Directory

Inclusion Criteria: 1. Locally advanced NSCLC (stages IIB, IIIA or IIIB of the TNM classification 7th edition) or trace metastatic stage IV (\</=5 mestastasis, \</= 3 organ reached) 2. Exclusive therapeutic management by concomitant radio-chemotherapy administered in accordance with international recommendations (dual therapy with platinum salts) 3. Signed consent 4. Patients affiliated with the social security scheme or beneficiary of a similar scheme. Exclusion Criteria: 1. Minor 2. Pregnant / lactating woman 3. Person deprived of liberty by judicial or administrative decision, adults who are the subject of a legal protection measure or unable to express their consent 4. Previous cancer in the 2 years prior to registration 5. Previousradiotherapy / thoracic surgery 6. Patients under experimental treatment or for whom the administration of an experimental treatment is planned 7. Claustrophobic patients 8. Severe Renal Insufficiency (Clearance MDRD Cockroft \<30ml / min) 9. Uncontrolled diabetes, hyperglycemia\> 1.8g / L 10. Patient with metallic implants not compatible with MRI or any immovable implanted electronic medical device (eg pacemaker, neurostimulator, cochlear implants, etc.)