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Fecal Microbiota Transplantation for Irritable Bowel Syndrome
Sponsor: Guangzhou First People's Hospital
Summary
Fecal microbiota transplantation (FMT) is a strategy that infuses a fecal suspension containing a healthy donor's microbiota into a patient's gut to restore his/her intestinal microbiome. FMT has a higher cure rate than standard antibiotic treatment for recurrent Clostridium difficile infections,and shows promising results in Inflammatory bowel disease（IBD）.However, few studies have evaluated whether FMT is effective to treat Irritable bowel syndrome(IBS).The investigators propose to determine the efficiency and safety of FMT in patients with Irritable bowel syndrome.
Official title: Efficacy and Safety of Fecal Microbiota Transplantation for Irritable Bowel Syndrome
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2018-08-10
Completion Date
2030-12-31
Last Updated
2021-08-03
Healthy Volunteers
No
Interventions
fecal microbiota transplantation
200 mL of prepared fecal microbiota suspension from heathy donors' fresh feces was injected into the colon
Infusion of sham
Infusion of sham
probiotics, antibiotics or antidepressants
Drugs such as probiotics, antibiotics, antidepressants
Locations (1)
Guangzhou First People's Hospital
Guangzhou, Guangdong, China