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Radiotracer-Based Perfusion Imaging of Patients With Peripheral Arterial Disease
Sponsor: Nationwide Children's Hospital
Summary
The aim of this clinical study is to 1) establish a healthy database for nuclear perfusion imaging of the lower extremities and 2) assess the prognostic value of radiotracer-based perfusion imaging for predicting clinical outcomes in patients with peripheral artery disease (PAD) who are undergoing lower extremity revascularization procedures. We hypothesize that radiotracer imaging of the lower extremities will provide a sensitive non-invasive imaging tool for quantifying regional abnormalities in skeletal muscle perfusion and evaluating responses to medical treatment.
Official title: Radiotracer Imaging of Skeletal Muscle Perfusion in Patients With Peripheral Artery Disease
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
192
Start Date
2017-02-17
Completion Date
2028-12-31
Last Updated
2025-04-01
Healthy Volunteers
Yes
Interventions
SPECT/CT perfusion imaging
Subjects will receive a standard clinical dose of a radionuclide for perfusion imaging of the lower extremities before and after revascularization procedures.
PET/CT perfusion imaging
Subjects will receive a standard clinical dose of a radionuclide for perfusion imaging of the lower extremities before and after revascularization procedures.
Locations (1)
Nationwide Children's Hospital
Columbus, Ohio, United States