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Evaluation of Trigeminal Nerve Blockade
Sponsor: University of Florida
Summary
Cleft palate repair requires high doses of opioids for pain control postop. An alternative approach is placement of nerve blocks in the pterygopalatine fossa bilaterally, blocking the maxillary nerve \& covering the entire midface. Application of bilateral suprazygomatic maxillary nerve blockade of the infraorbital nerve may provide effective analgesia for cleft lip repair, improving time to oral intake, pain control and time to hospital discharge.
Official title: Evaluation of Trigeminal Nerve Blockade in the Pterygopalatine Fossa for Cleft Palate Repair: a Pilot Study
Key Details
Gender
All
Age Range
3 Months - 5 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2018-11-20
Completion Date
2027-10-30
Last Updated
2026-01-20
Healthy Volunteers
No
Interventions
Ropivacaine
A single injection into the pterygopalatine fossa bilaterally of 0.2% ropivacaine at a dose of 0.15 mL/kg (block) after the induction of general anesthesia
Sham Comparator
The subcutaneous placement of a 25 Gauge needle as a sham control after the induction of general anesthesia. Nothing will be injected.
Locations (1)
UF Health
Gainesville, Florida, United States