Clinical Research Directory

Inclusion Criteria: * Women with a pregnancy and a history of at least one spontaneous preterm birth before 34+0 weeks and/or a history of late abortion * 12+0 -18+0 weeks of gestation * Minimal age of 18 years * Informed consent signature Exclusion Criteria: * The previous preterm delivery is iatrogenic proterm labor * Major fetal abnormalities (requiring surgery or leading to infant death or severe handicap) * The pregnant woman with severe cervical erosion, cervical polyp, hemorrhage and the doctors think she could not use cerclage pessary * The pregnant woman with uterine cervicitis * The pregnant woman that has been confirmed premature birth * Cerclage prior to randomisation * Cerclage prior to randomisation * Placenta previa totalis * Active vaginal bleeding at the moment of randomization * Spontaneous rupture of membranes at the time of randomization * Silicone allergy * Painful regular uterine contractions * The pregnant woman have the indication of operation cervical cerclage * Current participation in other RCT