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Genetics Of Autoimmunity In Type I Diabetes
Sponsor: Medical College of Wisconsin
Summary
The purpose of this study is to gain more information about the step-by-step process that causes someone to develop type 1 diabetes. Scientists think that a person's own immune system, directed by genetic and environmental factors play a major role in its development. Participation involves a blood draw, a brief medical history questionnaire and measurements of height and weight. Some participants will be asked to return for annual follow-up visits for 10 years.
Key Details
Gender
All
Age Range
2 Years - Any
Study Type
OBSERVATIONAL
Enrollment
4000
Start Date
2001-08
Completion Date
2050-01
Last Updated
2026-03-16
Healthy Volunteers
Yes
Interventions
Blood Collection
Blood will be collected via venipuncture and analyzed. Blood samples will be analyzed for HLA haplotype (a genetic sequence related to type 1 diabetes susceptibility), plasma-induced signature, diabetes autoantibodies, complete blood count with differential, and serum and plasma for storage. For family members with diabetes, blood will also be tested for A1c.
Locations (1)
Medical College of Wisconsin
Milwaukee, Wisconsin, United States