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NOT YET RECRUITING
NCT03653702
PHASE1

Radiation-Free Technique for Evaluating Renal Scarring (RAFTERS)

Sponsor: Boston Children's Hospital

View on ClinicalTrials.gov

Summary

In this research study the investigators want to study a safe, radiation-free technique known as contrast-enhanced ultrasound that may improve the ability to diagnose or evaluate renal scarring compared to regular ultrasound. This technique requires injection into a vein of a small amount of contrast material called Lumason. Contrast material is a type of dye that helps the investigators image the structures in the body more clearly. If this technique is successful, the need for DMSA studies may be avoided to diagnose or evaluate kidney scarring. DMSA is a more expensive test, causes radiation exposure, may require sedation and/or injection of contrast agents with the potential to cause allergic reactions.

Key Details

Gender

All

Age Range

6 Months - 35 Years

Study Type

INTERVENTIONAL

Enrollment

70

Start Date

2027-07-01

Completion Date

2029-07

Last Updated

2026-07-22

Healthy Volunteers

No

Interventions

DRUG

Sulfur Hexafluoride Lipid Type A Microspheres 25 MG Injection Powder for Suspension [LUMASON]

Lumason will be used as the contrast agent. Standard Lumason dose will be used: 0.03mL/kg up to a maximum dose of 2.4 milliliter (mL) per injection

Locations (1)

Boston Children's Hospital

Boston, Massachusetts, United States