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Microwave Ablation Versus Stereotactic Body Radiotherapy for Colorectal Liver Metastases in Oligometastatic Disease: a Prospective, Randomised, Phase 2 Trial
Sponsor: Rigshospitalet, Denmark
Summary
The LAVA-CRLM trial (Local Ablation Versus Ablative radiotherapy in ColoRectal Liver Metastases) is a prospective, randomised, phase 2 study designed to compare local control and safety of microwave ablation (MWA) versus stereotactic body radiotherapy (SBRT)in patients with colorectal liver metastases and oligometastatic disease. Primary endpoint is freedom form local lesion progression.
Official title: Stereotactic Body Radiation Therapy vs. Microwave Ablation for Colorectal Cancer Patients With Metastatic Disease in the Liver - a Randomized Phase II Trail
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2018-07-25
Completion Date
2029-12-03
Last Updated
2026-03-19
Healthy Volunteers
No
Conditions
Interventions
MWA
Patients are allocated to one of the two arms in a 1:1 randomization
SBRT
Patients are allocated to one of the two arms in a 1:1 randomization
Locations (1)
Righospitalet
Copenhagen, Denmark