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RECRUITING
NCT03662373

Innovative SolutIons for DosimEtry in Hadrontherapy (INSIDE)

Sponsor: CNAO National Center of Oncological Hadrontherapy

View on ClinicalTrials.gov

Summary

The study aim is to test the clinical feasibility and effectiveness of an online qualitative monitoring device named INSIDE system during hadrontherapy treatments. This instrumentation is composed by detectors able to acquire secondary signals generated by the interaction of the primary beam with human tissues. From these measurements performed during irradiation, the INSIDE system estimates the particle beam range inside the patient's body and check the compliance of the ongoing treatment with the clinical prescription, with the aim to optimize the delivered dose. The study aims to longitudinally monitor patients treated with hadrontherapy at the Italian National Centre of Oncological Hadrontherapy (CNAO) in Pavia in order to: * evaluate the stability of the INSIDE system response and the significance of the monitoring measurement; * study the clinical tolerances between ongoing and prescribed treatments within which the differences in particle range are not clinically relevant; * assess what impact an instrument such as the INSIDE system can have on the clinical routine; * evaluate the benefits of such a monitoring system with respect to treatment planning constraints.

Official title: Sperimentazione Clinica Del Sistema INSIDE - Innovative SolutIons for DosimEtry in Hadrontherapy - Per il Monitoraggio Del Trattamento in Adroterapia

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

40

Start Date

2019-07-16

Completion Date

2025-12-31

Last Updated

2025-08-11

Healthy Volunteers

No

Interventions

RADIATION

carbon ions radiation therapy

Carbon ion radiation therapy to treat adenoid cystic carcinoma, skull base (clivus) chordoma.

RADIATION

protons radiation therapy

Proton radiation therapy used to treat meningioma and squamocellular rhinopharynx carcinoma

Locations (1)

CNAO

Pavia, Pavia, Italy