Clinical Research Directory

Inclusion Criteria: * Men aged greater than equal to18 with histologically confirmed primary prostate cancer. * KPS greater than equal to 70 * Patient with a negative staging bone scan. * Patient can undergo an MRI. * Patient with negative staging CT or MRI of pelvis. Suspicious evidence of nodal involvement on staging CT or MRI of pelvis is defined as greater than 1 cm on short axis. Documented negative biopsy of suspicious node required. * Patient is medically fit to undergo prostatectomy. * Patient has either Gleason Score greater than equal to 8 on biopsy and/or clinical/radiographic evidence of T3 disease. Exclusion Criteria: * Prior history of receiving pelvic radiotherapy. * Patient is unwilling to undergo prostatectomy. * Patient with active inflammatory bowel disease defined as currently receiving therapy for IBD.