Clinical Research Directory

Inclusion Criteria: 1. Female 2. 18 years of age or greater and 90 years of age or less 3. One or more of the following indications for fCO2 laser treatment: 1. Genitourinary symptoms of menopause, including after natural, medical- induced or surgical menopause 2. Vaginal dryness, burning, itching or dyspareunia not related to menopause 3. Stress urinary incontinence 4. Recurrent urinary tract infections (UTIs), defined as 4 or more in a year 5. Overactive bladder 4. Must sign the informed consent 5. Must be willing to comply with the study protocol Exclusion Criteria: 1. Contraindications to fCO2 laser treatment, such as: 1. Currently implanted synthetic pelvic mesh, sling or tape 2. Current or previous genital cancers 3. Radiation to the vaginal or colo-rectal tissue 4. Currently pregnant or less than 3 months following pregnancy 5. Undiagnosed vaginal or cervical lesions 2. Patients who have received vaginal fCO2 laser treatment within the past 12 months 3. Patients treated with vaginal estrogen within the past 3 months 4. Patients with undiagnosed vaginal bleeding 5. Active vulvar or vaginal infection, including herpes, candidiasis, etc. 6. Current urinary tract infection (UTI), confirmed by positive urine culture and patient-reported symptoms 7. Pelvic or vaginal surgery with the past 9 months 8. Pelvic organ prolapse beyond the introitus 9. Patient possesses any other characteristics that, per the investigator's judgment, deems them unsuitable (i.e. may increase the patient's risk, may affect the conduct of the study etc.) for the treatment and/or study 10. Participation in an investigational trial that used a study treatment, medication and/or biologic within 6 months or less prior to the date of the screening visit