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ENROLLING BY INVITATION
NCT03681977
NA

Clinical Outcomes of MP Persona vs. Persona Knee-PS

Sponsor: Lady Davis Institute

View on ClinicalTrials.gov

Summary

Knee osteoarthritis (OA) is a highly prevalent condition that results in substantial pain and loss of function. The end stage treatment for knee OA is total knee arthroplasty (TKA), a common and safe procedure typically performed for relief of symptoms. However, an increasing number of patients are complaining about their TKA due to altered sensations between their previous joint and the implant. Although several designs have been proposed to improve these outcomes, the knee kinematics after TKA remains different from physiological kinematics. The Medial Pivot TKA design was introduced to closely mimic normal knee kinematics and create the natural feeling of the knee. This study is intended to evaluate the clinical effectiveness and ability to restore knee motion of two TKA devices: the Medial Pivot Persona TKA Zimmer design with the traditional Zimmer Persona Knee-PS. The investigator's hypothesis is that the Medial Pivot design will results in better patient outcomes and restore knee motion at natural parameters.

Official title: The Influence of Medial Pivot Knee Arthroplasty Implant Design on Joint Mechanics, Muscle Activation and Clinical Outcomes

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

162

Start Date

2019-09-01

Completion Date

2026-06-30

Last Updated

2024-07-12

Healthy Volunteers

Yes

Interventions

DEVICE

Zimmer MP Persona

The medial pivot Persona® knee implant with a Medial Congruent™ Bearing

DEVICE

Zimmer Persona Knee-PS

Persona the personalized knee system

Locations (3)

Montreal General Hospital

Montreal, PQ, Canada

Lethbridge-Layton-MacKay Rehabilitation Centre

Montreal, PQ, Canada

Jewish General Hospital

Montreal, PQ, Canada