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ACTIVE NOT RECRUITING
NCT03690089
PHASE2

Low-dose Atropine Eye Drops to Reduce Progression of Myopia in Children in the United Kingdom

Sponsor: Belfast Health and Social Care Trust

View on ClinicalTrials.gov

Summary

Short-sightedness, also called myopia, makes objects in the distance, such as the television, look blurred. This is caused by the eye growing too long, something that usually happens while children are also getting taller. People with myopia can see better with glasses or contact lenses, but this doesn't stop their eyes continuing to become more short-sighted. The CHAMP UK study is investigating a type of eye drop called atropine that might help to stop myopia getting worse as children get older.

Official title: Low-dose Atropine Eye Drops to Reduce Progression of Myopia in Children: a Multi-centre Placebo Controlled Randomised Trial in the United Kingdom

Key Details

Gender

All

Age Range

6 Years - 12 Years

Study Type

INTERVENTIONAL

Enrollment

289

Start Date

2019-04-03

Completion Date

2027-02-02

Last Updated

2023-09-07

Healthy Volunteers

Yes

Conditions

Interventions

DRUG

Atropine Sulfate

Atropine sulfate 0.01% eye drops which consist of 10mls of a clear colourless solution of atropine sulfate 0.01% w/v and benzalkonium chloride 0.01% w/v in sterile water.

OTHER

Placebo

Placebo eye drops which consist of 10mls of a clear colourless solution of benzalkonium chloride 0.01% w/v in sterile water.

Locations (4)

Northern Ireland Clinical Research

Belfast, United Kingdom

Aston University Eye Clinic

Birmingham, United Kingdom

Anglia Ruskin University Eye Clinic

Cambridge, United Kingdom

Centre for Living (Glasgow Caledonian University)

Glasgow, United Kingdom