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COMPLETED
NCT03691714
PHASE2

Durvalumab (MEDI4736) With Cetuximab in Previously Treated Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Sponsor: Trisha Wise-Draper

View on ClinicalTrials.gov

Summary

The purpose of this research study is to test the combination of the anti-cancer drugs durvalumab, the study drug, and cetuximab as a treatment for metastatic or recurrent head and neck cancer. Participants will receive both durvalumab and cetuximab.

Official title: An Open-label, Phase II Study of Durvalumab (MEDI4736) in Combination With Cetuximab in Previously Treated Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC)

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

35

Start Date

2018-10-23

Completion Date

2024-12-01

Last Updated

2026-06-26

Healthy Volunteers

No

Interventions

DRUG

Durvalumab

Two hour infusion

DRUG

Cetuximab

Two hour infusion for loading dose followed by weekly one hour infusion

Locations (1)

UC Health

Cincinnati, Ohio, United States