Clinical Research Directory
Browse clinical research sites, groups, and studies.
Randomized Controlled Trial for Ankle Fracture Pain Control
Sponsor: Lahey Clinic
Summary
This project is a multicenter, three armed, prospective randomized control trial studying the effectiveness of a long-acting local anesthetic "cocktail" in patients undergoing operative fixation of ankle fractures.
Official title: A Prospective, Randomized Trial Evaluating Regional Anesthesia, Long-Acting Local Anesthesia, and Traditional Care for Pain Control of Operatively Treated Ankle Fractures
Key Details
Gender
All
Age Range
18 Years - 89 Years
Study Type
INTERVENTIONAL
Enrollment
70
Start Date
2020-09-01
Completion Date
2027-09-01
Last Updated
2025-11-06
Healthy Volunteers
No
Conditions
Interventions
Long-Acting Local Anesthesia
The cocktail consists of: * 0.5% Ropivicaine, 24.6 mL * Clonidine 100 mcg/mL, 0.4mL * Epinephrine 1mg/mL, 0.5mL * Saline to total volume of 50 mL (24.5mL of saline) The total amount of solution prepared is 50mL, but typically 30mL is used based on the size of the incision. The total volume administered will be recorded.
Regional Anesthesia
0.5% ropivicaine - 30mL each sciatic and femoral/saphenous nerve, ultrasound guided
Locations (1)
Lahey Hospital & Medical Center
Burlington, Massachusetts, United States