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RECRUITING
NCT03696199
PHASE4

Randomized Controlled Trial for Ankle Fracture Pain Control

Sponsor: Lahey Clinic

View on ClinicalTrials.gov

Summary

This project is a multicenter, three armed, prospective randomized control trial studying the effectiveness of a long-acting local anesthetic "cocktail" in patients undergoing operative fixation of ankle fractures.

Official title: A Prospective, Randomized Trial Evaluating Regional Anesthesia, Long-Acting Local Anesthesia, and Traditional Care for Pain Control of Operatively Treated Ankle Fractures

Key Details

Gender

All

Age Range

18 Years - 89 Years

Study Type

INTERVENTIONAL

Enrollment

70

Start Date

2020-09-01

Completion Date

2027-09-01

Last Updated

2025-11-06

Healthy Volunteers

No

Conditions

Interventions

DRUG

Long-Acting Local Anesthesia

The cocktail consists of: * 0.5% Ropivicaine, 24.6 mL * Clonidine 100 mcg/mL, 0.4mL * Epinephrine 1mg/mL, 0.5mL * Saline to total volume of 50 mL (24.5mL of saline) The total amount of solution prepared is 50mL, but typically 30mL is used based on the size of the incision. The total volume administered will be recorded.

DRUG

Regional Anesthesia

0.5% ropivicaine - 30mL each sciatic and femoral/saphenous nerve, ultrasound guided

Locations (1)

Lahey Hospital & Medical Center

Burlington, Massachusetts, United States