Clinical Research Directory

Inclusion Criteria: * Age \> 18 years, no upper age limit * Karnofsky Performance Score \> 50 points * Expected Survival \> 3 months * 1-10 cerebral metastases of metastatic solid cancer * Indication for local radiotherapy * Patients must be able to understand the protocol and provide informed consent Exclusion Criteria: * Whole Brain radiotherapy no longer than 6 weeks before the start of stereotactic radiotherapy or planned whole brain radiotherapy after stereotactic radiotherapy * Prior irradiation of the cerebral metastasis that is to be treated in the study * Relevant overlap of prior radiation fields with the metastasis that is to be treated in the study * Metastasis in the brainstem * Contraindication for cerebral MRI * Metastasis that is to be treated in the study can't be visualized in contrast-enhanced T1 MRI sequence * Pregnant or lactating women * Abuse of illicit drugs, alcohol or medication * Patient not able or willing to behave according to protocol * Participation in another clinical trial