Clinical Research Directory

Inclusion Criteria: 1. All patients who successfully underwent lung transplant at the University of Virginia. 2. Followed by medical lung transplant team for post-lung transplant rejection surveillance program at the University of Virginia. 3. Subjects with co -morbid illnesses such as neurologic, liver and or kidney or GI tract disease/ dysfunction are not excluded 4. Clinically stable to undergo MRI Imaging Exclusion Criteria: 1. Continuous oxygen use at home if decided to consent for MRI imaging 2. Blood oxygen saturation of less than 92%as measured by pulse oximetry on the day of imaging if decided to consent for MRI imaging. 3. Forced Expiratory Volume in 1 second (FEV1) percent predicted less than 25% if decided to consent for MRI imaging. 4. Pregnancy or lactation if decided to consent for MRI imaging. 5. Claustrophobia, inner ear implants, aneurysm or other surgical clips, metal foreign bodies in eye, pacemaker or other contraindication to MR scanning. Subjects with any implanted device that cannot be verified as MRI compliant will be excluded if decided to consent for MRI imaging. 6. Chest circumference greater than that of the xenon MR and/or helium coil. The circumference of the coil is approximately 42 inches if decided to consent for MRI imaging. 7. History of congenital cardiac disease, chronic renal failure, or cirrhosis if decided to consent for MRI imaging. 8. Inability to understand simple instructions or to hold still for approximately 10 seconds if decided to consent for MRI imaging. 9. History of respiratory infection within 2 weeks prior to the MR scan if decided to consent for MRI imaging. 10. History of MI, stroke and/or poorly controlled hypertension if decided to consent for MRI imaging.