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Tocotrienols for Obesity of Postmenopausal Women
Sponsor: Texas Tech University Health Sciences Center
Summary
Postmenopausal women are at a risk of excessive weight gain, bone loss, hypertension, and metabolic syndrome. Obesity-induced chronic low-grade inflammation is initiated by excess nutrients in metabolic cells. Recent studies have indicated tocotrienols (one kind of vitamin E, a potent antioxidant) supplement may be good for mitigating negative impacts of obesity in postmenopausal women. The purpose of the study is to examine the effect of 24-week tocotrienols on obesity-associated outcome measurements in postmenopausal women. The investigators will enroll 60 qualified women at the start of the study and randomly assigned to no tocotrienols (placebo) or tocotrienols group for 24 weeks. Obesity-associated measurements will be recorded using blood, urine, adipose tissue, and fecal samples. All data will be analyzed statistically.
Official title: Actions of Dietary Tocotrienols on Obesity
Key Details
Gender
FEMALE
Age Range
Any - Any
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2019-03-15
Completion Date
2025-12-30
Last Updated
2025-03-28
Healthy Volunteers
Yes
Conditions
Interventions
placebo softgel
Each placebo softgel of 430 mg olive oil will contain no TT or tocopherols at detectable levels.
DeltaGold® Tocotrienol 70%
DeltaGold® Tocotrienol 70% contains 430 mg tocotrienol (90% δ-tocotrienol + 10% γ-tocotrienol) with a 70% purity, representing 300 mg tocotrienol.
Locations (1)
Texas Tech University Health Sciences Center
Lubbock, Texas, United States