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Vasopressin in Intraabdominal Pressure Elevation
Sponsor: The Cleveland Clinic
Summary
The aim of this study is to investigate any direct correlation between increased intrathoracic pressure, intraabdominal pressure and intracranial pressure, following a controlled elevation in intraabdominal pressure and intrathoracic pressure (PEEP). The second end-point is to investigate any correlation between elevated intracranial pressure and vasopressin release, urine output and urine and serum osmolality by measuring their values at different time-points.
Official title: Correlation Between Vasopressin and Renal Function Following a Controlled Intraabdominal Pressure Elevation
Key Details
Gender
All
Age Range
18 Years - 72 Years
Study Type
INTERVENTIONAL
Enrollment
16
Start Date
2017-04-28
Completion Date
2024-12-31
Last Updated
2026-04-29
Healthy Volunteers
Yes
Interventions
Study Arm
Measurements of optic nerve diameter, serum and urine osmolarity, serum vasopressin
Locations (1)
Cleveland Clinic Florida
Weston, Florida, United States