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COMPLETED
NCT03707054
NA

Vasopressin in Intraabdominal Pressure Elevation

Sponsor: The Cleveland Clinic

View on ClinicalTrials.gov

Summary

The aim of this study is to investigate any direct correlation between increased intrathoracic pressure, intraabdominal pressure and intracranial pressure, following a controlled elevation in intraabdominal pressure and intrathoracic pressure (PEEP). The second end-point is to investigate any correlation between elevated intracranial pressure and vasopressin release, urine output and urine and serum osmolality by measuring their values at different time-points.

Official title: Correlation Between Vasopressin and Renal Function Following a Controlled Intraabdominal Pressure Elevation

Key Details

Gender

All

Age Range

18 Years - 72 Years

Study Type

INTERVENTIONAL

Enrollment

16

Start Date

2017-04-28

Completion Date

2024-12-31

Last Updated

2026-04-29

Healthy Volunteers

Yes

Interventions

DIAGNOSTIC_TEST

Study Arm

Measurements of optic nerve diameter, serum and urine osmolarity, serum vasopressin

Locations (1)

Cleveland Clinic Florida

Weston, Florida, United States