Clinical Research Directory
Browse clinical research sites, groups, and studies.
Multi-Omic Assessment of Squamous Cell Cancers Receiving Systemic Therapy
Sponsor: University Health Network, Toronto
Summary
This is prospective research study which will include patients with recurrent or metastatic squamous cell carcinoma of the head and neck, esophagus and anal canal starting on first-line platinum based chemotherapy or any line of immunotherapy treatment.This study aims to characterize the dynamic changes in genomic, epigenetic, immune profiling and imaging data during treatment with systemic therapy. Patients will have archived tumor samples requested as well as blood samples collected at up to four time points to analyze these changes. Imaging data will be derived from patients' routine CT scans before and after treatment.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
39
Start Date
2018-11-06
Completion Date
2027-01
Last Updated
2026-01-08
Healthy Volunteers
No
Conditions
Locations (1)
Princess Margaret Cancer Centre
Toronto, Ontario, Canada