Clinical Research Directory
Browse clinical research sites, groups, and studies.
High Dose Vitamin A in Preventing Gastrointestinal GVHD in Participants Undergoing Donor Stem Cell Transplant
Sponsor: Ohio State University Comprehensive Cancer Center
Summary
This phase I trial studies the side effects and how well high dose vitamin A works in preventing gastrointestinal graft versus host disease (GVHD) in participants undergoing donor stem cell transplant. Vitamin A deficiency is associated with increased risk of gastrointestinal GVHD. Vitamin A regulates growth and differentiation of intestinal cells and may reduce risk of gastrointestinal GVHD.
Official title: Single, High Dose Vitamin A Replacement in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
62
Start Date
2020-02-07
Completion Date
2026-12-31
Last Updated
2025-07-11
Healthy Volunteers
No
Interventions
Vitamin A Compound
Given PO or enterally
Best Practice
Receive usual care
Locations (1)
Ohio State University Comprehensive Cancer Center
Columbus, Ohio, United States