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Disorders of the Acute Phase Response Following Trauma and Invasive Surgery
Sponsor: Vanderbilt University Medical Center
Summary
The purpose of the proposed study is to test these hypotheses through the following aims: 1. To determine if early plasmin activation following severe injury correlates with SIRS, TIC and complications throughout convalescence in both trauma and surgical patients. 2. To determine if early plasmin activation following severe injury correlates with plasminogen consumption and poor plasmin activity later in convalescence.
Official title: Disorders of the Acute Phase Response Accelerated by Plasmin Activation Following Trauma and Invasive Surgery: A Prospective Study
Key Details
Gender
All
Age Range
2 Months - Any
Study Type
INTERVENTIONAL
Enrollment
320
Start Date
2019-12-12
Completion Date
2027-12-31
Last Updated
2026-03-27
Healthy Volunteers
Yes
Conditions
Interventions
Blood draw (venipuncture or fingerstick)
Blood will be drawn from participants by venipuncture and/or by fingerstick. Finger sticks will not be collected in the pediatric population.
Locations (1)
Vanderbilt Univeristy Medical Center
Nashville, Tennessee, United States