Clinical Research Directory
Browse clinical research sites, groups, and studies.
Evaluation of the Personal KinetiGraph™ (PKG™) to Improve Insight Into Parkinson's Disease Status
Sponsor: Global Kinetics Corporation
Summary
The primary objective is to understand the utility of Personal KinetiGraph movement recording system data in the clinical management of Parkinson's disease (PD) in routine clinical care at a movement disorders clinic. Specifically: 1. Measure medication use and clinical management plan changes in a large, multicenter cohort among participants undergoing a clinical assessment with an MDS in which the MDS reviews the participant's PKG during the clinical assessment in half of the enrolled participants (PKG + Group) and in half of the enrolled participants the MDS completes the clinical assessment without the PKG (PKG- Group). 2. Determine the association between frequency of medication changes, the PKG information, and other clinical assessments among participants with and without a PKG report of their PD motor status available to the clinician at the time of evaluation.
Official title: Evaluation of the Personal KinetiGraph™ (PKG™) to Improve Insight Into Parkinson's Disease Status (APPRISE)
Key Details
Gender
All
Age Range
46 Years - 83 Years
Study Type
INTERVENTIONAL
Enrollment
231
Start Date
2017-05-17
Completion Date
2025-10
Last Updated
2025-09-04
Healthy Volunteers
No
Conditions
Interventions
Personal KinetiGraph™ (PKG™)
The Personal KinetiGraph™ (PKG™) Movement Recording System was developed by neurologists at the Melbourne-based Florey Institute of Neuroscience and Mental Health. The product is manufactured and marketed by Global Kinetics (GKC). The Personal KinetiGraph™ (PKG™) Movement Recording System consists of the following: * A wrist-worn data logger designed to acquire data on the kinematics of movement disorder symptoms over a 6-10 day period. * An application to configure the data logger and transfer the acquired data at the end of a recording. * A series of algorithms that analyze the uploaded data, producing a report that is delivered to the clinician. The report contains objective data distinguishing the movement patterns consistent with tremor, bradykinesia, dyskinesia and immobility.
Locations (12)
Sutter Health
Sacramento, California, United States
University of California
San Diego, California, United States
Parkinson's Disease and Movement Disorders Center
Boca Raton, Florida, United States
University of Florida
Gainesville, Florida, United States
University of Miami
Miami, Florida, United States
University of South Florida
Tampa, Florida, United States
University of Kansas Medical Center
Kansas City, Kansas, United States
Johns Hopkins Medical Institute
Baltimore, Maryland, United States
Michigan State University
East Lansing, Michigan, United States
Northwell Health
Great Neck, New York, United States
New York University
New York, New York, United States
University of Texas
Houston, Texas, United States