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RECRUITING
NCT03750513
PHASE1

LET Optimized IMPT in Treating Pediatric Patients With Ependymoma

Sponsor: M.D. Anderson Cancer Center

View on ClinicalTrials.gov

Summary

This phase I trial studies the side effects of linear energy transfer (LET) optimized image modulated proton therapy (IMPT) in treating pediatric patients with ependymoma. Radiation therapy such as LET optimized IMPT, uses proton beams to kill tumor cells and shrink tumors without damaging surrounding normal tissues.

Official title: Pilot Trial of LET Optimized IMPT for Pediatric Patients With Ependymoma

Key Details

Gender

All

Age Range

Any - 22 Years

Study Type

INTERVENTIONAL

Enrollment

48

Start Date

2019-04-01

Completion Date

2027-12-31

Last Updated

2025-11-13

Healthy Volunteers

No

Interventions

RADIATION

Linear Energy Transfer-Optimized Intensity Modulated Proton Therapy

Given LET optimized IMPT

OTHER

Quality-of-Life Assessment

Ancillary studies

OTHER

Questionnaire Administration

Ancillary studies

Locations (2)

Massachusetts General Hospital Cancer Center

Boston, Massachusetts, United States

M D Anderson Cancer Center

Houston, Texas, United States