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Cancer Driving Mutations in Endometriosis Lesions and Development of Progesterone Resistance
Sponsor: Johns Hopkins University
Summary
This study will test the hypothesis that the molecular changes present in ectopic endometriosis lesions correlate with progesterone-resistant disease (using the criteria defined in this study) and are present in matched eutopic endometrium.
Official title: Prospective Clinical Study of the Relationship Between Cancer Driving Mutations Found in Endometriotic Implants and the Development of Progesterone Resistance
Key Details
Gender
FEMALE
Age Range
18 Years - 45 Years
Study Type
OBSERVATIONAL
Enrollment
135
Start Date
2020-10-01
Completion Date
2026-10-01
Last Updated
2025-06-26
Healthy Volunteers
Not specified
Conditions
Locations (3)
Yale School of Medicine
New Haven, Connecticut, United States
Johns Hopkins Hospital
Baltimore, Maryland, United States
Vanderbilt University Medical Center
Nashville, Tennessee, United States