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Sweden Cancerome Analysis Network - Breast Recurrence (SCAN-B-rec)
Sponsor: Lund University Hospital
Summary
Prospective multicenter observational study to assess molecular drivers of metastatic breast cancer and disease evolution upon therapeutic pressure. The main aim is to develop and validate prognostic, predictive and pathogenic markers in clinically well-characterized population-based material of breast cancer tumors and the corresponding normal tissue.These data will be used to characterize recurrent breast cancer on a molecular level, study tumor evolution, develop biomarkers of response/resistance to targeted therapy in the metastatic setting, enroll patients on targeted treatment clinical studies and to elucidate mechanisms of resistance to therapy.
Official title: SCAN-B-rec: Infrastructure, Technology Platform and Clinical Research Development to Profile and Monitor Metastatic Breast Cancer
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
2000
Start Date
2019-01-21
Completion Date
2030-12-01
Last Updated
2025-09-16
Healthy Volunteers
No
Conditions
Interventions
Biopsies, blood
We will perform targeted exon sequencing on paraffin embedded tissues from metastatic breast cancer
Locations (2)
Lund University Hospital
Lund, Sweden
Lund University Hospital
Lund, Sweden