Clinical Research Directory
Browse clinical research sites, groups, and studies.
Continuous Erector Spinae Block Versus Continuous Paravertebral Block
Sponsor: Boston Children's Hospital
Summary
Overall Aim: To evaluate the efficacy of continuous erector spinae block (ESB) versus continuous paravertebral block (PVB) for postoperative analgesia in children and adolescents undergoing surgical procedures via unilateral thoracotomy. Hypothesis: The investigators hypothesize that ESP block efficacy is not inferior to that of PVB with respect to pain control and consumed opiate equivalents at 24 hours postoperatively.
Official title: Continuous Erector Spinae Block Versus Continuous Paravertebral Block Following Thoracotomy: A Randomized, Controlled Non-Inferiority Study
Key Details
Gender
All
Age Range
1 Month - 12 Years
Study Type
INTERVENTIONAL
Enrollment
34
Start Date
2019-04-16
Completion Date
2025-02-01
Last Updated
2026-05-13
Healthy Volunteers
Yes
Conditions
Interventions
continuous erector spinae block (ESB)
Erector spinae block: T4/5 transverse process is identified with the ultrasound transducer in a parasagittal orientation; the needle tip is advanced until it contacts the transverse process, just below the erector spinae muscle complex; the erector spinae muscle is visualized to be elevated up off of the transverse process with normal saline injection. Following a bolus injection of 2ml/kg of 0.2% ropivacaine, a catheter is threaded into the space occupied by the local anesthetic bolus.
continuous paravertebral block (PVB)
The paravertebral space (bound medially by the bodies of the vertebrae, intervertebral discs, and intervertebral foraminae; anterolaterally by the parietal pleura and the innermost intercostal membrane; posteriorly by the transverse processes of the thoracic vertebrae, heads of the ribs, and the superior costotransverse ligament) laying between T4/5 is identified using the ultrasound transducer in a transverse orientation; the needle tip is advanced until it is seen passing under the transverse process, immediately superior to the pleura; the pleura is seen to deflect downward with normal saline injection. Following a bolus injection of 2ml/kg of 0.2% ropivacaine, a catheter is threaded into the space occupied by the local anesthetic bolus.
Ropivacaine
Ropivacaine 0.2% will be the drug used for each group (ESB group and PVB group)
Locations (1)
Boston Children"S Hospital
Boston, Massachusetts, United States