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Acute Maternal Hyperoxygenation for Fetal Transposition of the Great Arteries (TGA)
Sponsor: The Hospital for Sick Children
Summary
This prospective study will examine whether transient maternal hyperoxygenation is useful as a diagnostic test to more accurately detect TGA patients with poor vs. good neonatal intra-cardiac mixing of blood, based on the in-utero response to oxygen exposure. This study is Health Canada regulated
Official title: Transposition of the Great Arteries: Prenatal Anatomical and Hemodynamic Findings Associated With Perinatal Outcomes
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
34
Start Date
2018-09-20
Completion Date
2023-12-31
Last Updated
2026-04-28
Healthy Volunteers
No
Conditions
Interventions
Oxygen gas
Brief maternal administration of 65-70% O2 via a face mask during the last trimester
Locations (1)
The Hospital For Sick Children
Toronto, Canada