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Five Year Oncological Outcome After CME for Sigmoid Colon Cancer
Sponsor: Nordsjaellands Hospital
Summary
Study based in existing databases investigating the causal oncological treatment effects of complete mesocolic excision on UICC stage I-III sigmoid colon cancer
Official title: Five Year Oncological Outcome After Complete Mesocolic Excision for Sigmoid Colon Cancer: a Population-based Cohort Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
920
Start Date
2008-06-01
Completion Date
2025-12-31
Last Updated
2024-06-26
Healthy Volunteers
No
Conditions
Interventions
Complete mesocolic excision
Based on the principles of CME. The inferior mesenteric artery (IMA) was divided at its origin from the aorta to perform central lymph nodes dissection along the IMA between the aorta and the branching of the left colic artery. Sigmoid resection included the complete sigmoid colon and resection of the upper part of the rectum to ensure sufficient perfusion of the colo-rectal anastomosis. To achieve sufficient distance at the proximal bowel resection margin, parts of the descending colon or even left hemicolectomy were performed at the surgeon's discretion.
Conventional colon resection
The patients underwent what was considered standard colon cancer resections in Denmark during the study period.