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Enhancing Renal Graft Function During Donor Anesthesia
Sponsor: Nazmy Edward Seif
Summary
Renal transplantation is now recognized as the treatment of choice for patients with end-stage renal disease. An optimum anesthetic regimen should enhance the function and perfusion of the transplanted kidney. The aim of this study is to assess \& compare the effectiveness of 3 different modalities in this respect: Mannitol, Dopamine and adequate hydration.
Official title: Renal Graft Functional Enhancement During Donor Anesthesia: A Comparative Study of 3 Modalities
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2018-12-20
Completion Date
2026-12
Last Updated
2026-01-12
Healthy Volunteers
No
Interventions
Mannitol infusion
Infusion of Mannitol 20% at a dose of 0.5 mg/kg to the renal graft donor after induction of anesthesia over 15 minutes.
Dopamine infusion
Infusion of Dopamine at a dose of 4 microg/kg/min to the renal graft donor after induction of anesthesia till ligation of the renal artery.
Adequate hydration
Infusion of Ringer Acetate at a rate of 15 ml/kg/hr to the renal graft donor after induction of anesthesia till ligation of the renal artery.
Locations (1)
Kasr Al-Ainy Hospital, Cairo University
Cairo, Egypt