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Carboxylesterase 1 Genetic Variation and Methylphenidate in ADHD
Sponsor: Icahn School of Medicine at Mount Sinai
Summary
The study team will determine the association between d,l-methylphenidate (MPH) therapeutic outcomes in ADHD patients and genetic variants of CES1 and reveal key associations between CES1 genotypes and the PK and PD of MPH.
Key Details
Gender
All
Age Range
6 Years - 17 Years
Study Type
INTERVENTIONAL
Enrollment
500
Start Date
2018-03-04
Completion Date
2025-08
Last Updated
2024-08-09
Healthy Volunteers
No
Interventions
Methylphenidate
study to determine dose
Locations (4)
University of Florida
Gainesville, Florida, United States
Icahn School of Medicine at Mount Sinai
New York, New York, United States
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States
Seattle Children's Hospital
Seattle, Washington, United States