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COMPLETED
NCT03783091
PHASE2

A Trial of Vitamin B12 in Septic Shock

Sponsor: Medical College of Wisconsin

View on ClinicalTrials.gov

Summary

This study will randomize 20 septic shock patients to receive either a single 5 gram dose of IV vitamin B12 (Cyanokit® Meridian Medical Technologies, Columbia, MD) versus placebo in addition to standard of care to test the feasibility of completing clinical and laboratory protocols.

Official title: A Phase II Double Blind Randomized Controlled Trial of High Dose Vitamin B12 in Septic Shock

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2019-08-05

Completion Date

2023-02-23

Last Updated

2026-05-27

Healthy Volunteers

No

Conditions

Interventions

DRUG

Hydroxocobalamin

Single IV administration of Vitamin B12

DRUG

Placebo

Single IV administration of saline

Locations (1)

Medical College of Wisconsin

Milwaukee, Wisconsin, United States