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Measuring the Effects of Complementary Therapies in Chronic Neuropathic Pain
Sponsor: Chantal Berna
Summary
The objective of the study is to a) assess the presence of a maladaptive stress response, a decreased pain modulation and any cognitive impairment in patients with chronic neuropathic pain in comparison to healthy controls. and b) evaluate the efficacy of a treatment of hypnosis and of an open label placebo on these neuro-cognitive factors and on clinical pain. This will be done through a) a prospective observational comparative study of patients (base line measures) with Healthy Controls (HC) and b) an Open label; randomised, hypnosis vs. open label placebo (OLP) vs. treatment as usual control design; with a second phase of exploratory cross-over.
Official title: A Randomized-controlled Clinical Trial of Hypnosis Versus Open Label Placebo for Chronic Neuropathic Pain With an Investigation of Neuro-cognitive Dysfunctions as Maintaining Factors and Therapeutic Targets
Key Details
Gender
All
Age Range
18 Years - 90 Years
Study Type
INTERVENTIONAL
Enrollment
72
Start Date
2018-11-15
Completion Date
2024-07-05
Last Updated
2026-05-28
Healthy Volunteers
Yes
Conditions
Interventions
Hypnosis
A 6 session course of individual hypnosis therapy will be offered.
Open label placebo
Ritual intake of 2 placebo capsules twice a day
Locations (1)
Lausanne University Hospital (CHUV)
Lausanne, Switzerland