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NCT03785093

Intestinal Microbiota on Allergy, Growth and Development

Sponsor: Chinese University of Hong Kong

View on ClinicalTrials.gov

Summary

There is growing evidence that microbial programming beginning in-utero can be a central component for a balanced development of innate immunity and optimal growth and development in newborns. However, the specific types of bacteria along with their cross-talk with maternal and fetal host factors are far from being clear. The investigators hypothesize microbial compositions at different body sites of pregnant women are associated with early-life microbiota of their offspring as well as growth, neurodevelopment and the development of allergic and neurocognitive disorders. This is a prospective birth cohort study involving Chinese mother-child pairs. The investigators will follow up 120 pregnant women from first trimester until childbirth, and the child until three years of age.

Official title: Intestinal Microbiota on Allergy, Growth and Development of the Next Generation in Hong Kong

Key Details

Gender

FEMALE

Age Range

18 Years - 45 Years

Study Type

OBSERVATIONAL

Enrollment

120

Start Date

2018-11-01

Completion Date

2026-06-30

Last Updated

2023-09-05

Healthy Volunteers

Yes

Conditions

Locations (1)

Prince of Wales Hospital

Hong Kong, Hong Kong, China, Hong Kong